Ampoule Filling And Sealing Machine Manufacturer And Supplier In Ghana

An Ampoule Filling and Sealing Machine is a critical piece of equipment for pharmaceutical manufacturers producing injectable formulations that require precise dosing, contamination control, and secure flame sealing. In Ghana, where pharmaceutical manufacturing is steadily expanding to meet domestic healthcare needs and export requirements, dependable ampoule filling and sealing solutions are essential for maintaining product quality and regulatory compliance.

Technogen Enterprise is an experienced manufacturer and supplier of ampoule filling and sealing machines for Ghana, offering equipment designed to deliver consistent filling accuracy, smooth sealing, and reliable operation across various production capacities. These machines are widely used in pharmaceutical formulation plants for filling liquid injectables into glass ampoules followed by flame sealing.

Designed for Pharmaceutical Manufacturing in Ghana

Pharmaceutical manufacturers in Ghana operate under strict CGMP requirements where injectable products must be filled and sealed under controlled conditions. The ampoule filling and sealing machine is engineered to meet these requirements by combining synchronized filling, gas flushing, and sealing operations within a compact and operator-friendly design.

The machine range is available in 4-head, 6-head, and 8-head configurations, allowing manufacturers to select a model based on required production output and future scalability. Each configuration is designed to maintain uniform performance and filling accuracy across all heads.

Filling and Sealing Working Principle

The ampoule filling and sealing machine integrates multiple operations into a continuous and synchronized process:

• Ampoules are manually loaded onto the infeed tray

• Ampoules are transferred to the filling station through a controlled transport mechanism

• Liquid is filled using diving nozzles to minimize foaming and spillage

• “No Ampoule – No Filling” system prevents wastage and ensures clean operation

• Optional pre-gassing and post-gassing systems displace oxygen using inert gas

• Filled ampoules are sealed using a draw jaw sealing mechanism

• A pusher mechanism transfers sealed ampoules to the outfeed tray

This coordinated process ensures accurate dosing, reduced product loss, and uniform sealing quality.

Key Functional Highlights

One of the defining strengths of this machine is its focus on process reliability and operator safety:

• No Ampoule – No Filling system to avoid liquid wastage

• Pre and post gassing arrangement to improve product stability

• Draw jaw sealing system for uniform and secure ampoule sealing

• Integrated pusher mechanism for smooth discharge of sealed ampoules

These features make the machine suitable for both routine production and validated pharmaceutical processes.

Salient Features

• CGMP-compliant machine design

• Special induction gear motor with worm gearbox for synchronized operation

• Machine frame constructed from AISI 304 stainless steel

• All liquid contact parts manufactured from AISI 316L

• Diving nozzles to prevent foaming and spillage

• Filling capacity up to 20 ml with minimal change parts

• Provision for pre-gassing and post-gassing systems

• Infeed and outfeed tray system for ampoule handling

• Integrated counting arrangement for production monitoring

• Emergency stop button for enhanced operator safety

Construction and Metallurgy

The ampoule filling and sealing machine is manufactured using pharmaceutical-grade materials to ensure hygiene, durability, and long service life.

• AISI 304 stainless steel is used for the machine frame and non-contact structures

• AISI 316L stainless steel is used for all liquid contact components

This construction ensures resistance to corrosion, ease of cleaning, and compatibility with injectable formulations.

Applications in Ghana’s Pharmaceutical Sector

Injectable Drug Manufacturing
Used for filling and sealing liquid injectables in glass ampoules.

Pharmaceutical Formulation Plants
Supports accurate dosing and sealing of sterile and non-sterile liquid formulations.

Contract Manufacturing Organizations
Ideal for third-party pharmaceutical production requiring validated ampoule packaging.

Export-Oriented Pharmaceutical Units
Helps meet international quality and packaging standards for injectable products.

Technical Specifications

Optional Add-On Features

• PLC with touchscreen HMI interface

• Toughened glass or acrylic safety cabinet

Applicable Industry

• Pharmaceuticals

Pharmaceutical manufacturers seeking an ampoule filling and sealing machine manufacturer and supplier in Ghana benefit from equipment designed for accurate filling, reliable sealing, and consistent operation. This machine supports controlled injectable production, reduces product loss, and enhances overall packaging efficiency, making it a suitable choice for pharmaceutical facilities aiming to strengthen quality assurance and production reliability within Ghana’s regulated manufacturing environment.